Reproduce in the smallest case
A bug in a full page is the same bug in a small one, and the small one is readable. Cutting the markup down to the element and its parent is the step that turns a hunt into a read.
Trust the render, not the file
A stylesheet that is cached, a build step that did not run, or a file you are not loading all look correct in the editor and wrong in the browser. Checking the loaded URL is the first move when nothing changes.