Rows and columns
A pandas table is called a DataFrame. Rows are usually days, and columns are things like open, high, low, and close. You grab a column by its name, and everything else happens on top of that.
Speed over spreadsheets
pandas does in seconds what takes minutes in Excel, and keeps working when the data gets too big for the spreadsheet to even open. A quant can pull years of prices and summarize the whole thing in a few lines.